Which of the following is NOT listed as associated with DIC in pregnancy?

Which of the following is NOT listed as associated with DIC in pregnancy?

• A. Placental Abruption
• B. Dead Fetus Syndrome
• C. Amniotic Fluid Embolism
• D. Gestational Diabetes Mellitus

Answer: (D)

Disseminated intravascular coagulation in pregnancy is driven by widespread activation of coagulation due to obstetric events that release tissue factor and procoagulants into the maternal circulation. Placental abruption exposes maternal blood to placental tissue, triggering massive coagulation and consumption of platelets and clotting factors, which can lead to severe bleeding. Dead fetus syndrome, where fetal demise occurs and products are released into maternal blood, can also provoke a coagulopathic state via thromboplastic material. Amniotic fluid embolism introduces fetal tissue factor and inflammatory mediators into the mother’s circulation, causing an abrupt DIC picture. Sepsis and severe preeclampsia with HELLP are additional known triggers. Gestational diabetes mellitus, while associated with various obstetric complications, is not typically listed as a direct trigger or common association for DIC in pregnancy.

Disseminated intravascular coagulation in pregnancy is driven by widespread activation of coagulation due to obstetric events that release tissue factor and procoagulants into the maternal circulation. Placental abruption exposes maternal blood to placental tissue, triggering massive coagulation and consumption of platelets and clotting factors, which can lead to severe bleeding. Dead fetus syndrome, where fetal demise occurs and products are released into maternal blood, can also provoke a coagulopathic state via thromboplastic material. Amniotic fluid embolism introduces fetal tissue factor and inflammatory mediators into the mother’s circulation, causing an abrupt DIC picture. Sepsis and severe preeclampsia with HELLP are additional known triggers.

Gestational diabetes mellitus, while associated with various obstetric complications, is not typically listed as a direct trigger or common association for DIC in pregnancy.