What is the normal cerebral glucose (GLC) consumption per minute?

What is the normal cerebral glucose (GLC) consumption per minute?

• A. 2 mL/100 g/min
• B. 3 mL/100 g/min
• C. 5 mL/100 g/min
• D. 6 mL/100 g/min

Answer: (C)

Cerebral glucose utilization at rest is a tightly regulated, high-demand process because the brain relies almost entirely on glucose for energy and has limited glucose stores. The commonly cited resting rate is about 5 milligrams of glucose per 100 grams of brain tissue each minute. This figure reflects the brain’s constant energy needs and explains why cerebral glucose use stays relatively steady under normal conditions. Among the options, the value around 5 per 100 g per minute best matches this well-established resting rate, making it the best choice. Values lower than that would underestimate the brain’s energy demand, while a higher value would exceed the typical resting rate seen in healthy adults.

Cerebral glucose utilization at rest is a tightly regulated, high-demand process because the brain relies almost entirely on glucose for energy and has limited glucose stores. The commonly cited resting rate is about 5 milligrams of glucose per 100 grams of brain tissue each minute. This figure reflects the brain’s constant energy needs and explains why cerebral glucose use stays relatively steady under normal conditions.

Among the options, the value around 5 per 100 g per minute best matches this well-established resting rate, making it the best choice. Values lower than that would underestimate the brain’s energy demand, while a higher value would exceed the typical resting rate seen in healthy adults.