In a 70-kg patient, 1 unit of platelet concentrate should increase the platelet count by approximately which range?

In a 70-kg patient, 1 unit of platelet concentrate should increase the platelet count by approximately which range?

• A. 2000 to 5000/mm3
• B. 5000 to 10000/mm3
• C. 15000 to 20000/mm3
• D. 20000 to 25000/mm3

Answer: (B)

When a standard unit of platelet concentrate is given to an average adult, the immediate rise in the circulating platelet count is about 5,000 to 10,000 platelets per microliter (per mm3) of blood. In a 70-kg patient, this reflects the typical incremental effect of one unit, assuming there isn’t ongoing loss or consumption of platelets. The range 5,000–10,000/μL captures the usual variability between individuals and platelets from different donors. Options lower than that (around 2,000–5,000/μL) underestimate the expected rise, while options well above (15,000–20,000/μL or 20,000–25,000/μL) exceed what one standard unit typically accomplish.

When a standard unit of platelet concentrate is given to an average adult, the immediate rise in the circulating platelet count is about 5,000 to 10,000 platelets per microliter (per mm3) of blood. In a 70-kg patient, this reflects the typical incremental effect of one unit, assuming there isn’t ongoing loss or consumption of platelets. The range 5,000–10,000/μL captures the usual variability between individuals and platelets from different donors.

Options lower than that (around 2,000–5,000/μL) underestimate the expected rise, while options well above (15,000–20,000/μL or 20,000–25,000/μL) exceed what one standard unit typically accomplish.